Cytokine production

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 39/39 (2006.01) A61K 39/395 (2006.01) C07K 14/52 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 15/64 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2089389

2089389 9203574 PCTABS00011 A process for identifying nucleotide sequences coding for a polypeptide exhibiting specific ruminant cytokine or cytokine receptor activity or a fragment thereof, which process includes providing a vector including a complementary DNA (cDNA) sequence derived from ruminant cells or an extract thereof capable of being expressed in a unicellular organism; a unicellular organism; and a DNA probe for a homologous cytokine; introducing the vector into the said unicellular organism; culturing the organism to express a polypeptide encoded therein; probing the organism with the DNA probe; and isolating a vector containing a cDNA sequence encoding for a polypeptide exhibiting specific ruminant cytokine or cytokine receptor activity.

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