C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) C07K 14/715 (2006.01) C12N 5/00 (2006.01) C12N 5/10 (2006.01) C12N 15/19 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2356779
Polynucleotides encoding the IL-13 receptor and fragments thereof are disclosed. IL-13 receptor proteins, methods for their production, inhibitors of binding of IL-13 and its receptor and methods for their identification are also disclosed. Methods of medical treatment using such molecules and antagonists of the IL-13/IL-13R interaction are also provided.
L'invention concerne des polynucléotides codant pour le récepteur de IL-13 et des fragments de ce dernier. Des protéines réceptrices de IL-13, leurs techniques de production, les inhibiteurs de liaison de IL-13 et de son récepteur, ainsi que leurs techniques d'identification sont également traités. L'invention concerne enfin des techniques de traitement médical utilisant les molécules et antagonistes de l'interaction de IL-13/IL-13R.
Collins Mary
Donaldson Debra
Fitz Lori
Neben Tamlyn
Whitters Matthew J.
Genetics Institute Inc.
Genetics Institute Llc.
Johns Hopkins University
Riches Mckenzie & Herbert Llp
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