Cytological and histological fixative composition and...

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G01N 1/30 (2006.01) C12Q 1/00 (2006.01) G01N 33/48 (2006.01) G01N 33/50 (2006.01) C12Q 1/24 (2006.01)

Patent

CA 2335747

The present invention is directed to a fixative composition, the use of the fixative composition in preparing cytological or histological specimens, and a method of preparing particulate matter, such as cytology, hematology and microbiology specimens, for examination by collecting the particulate matter in a uniform layer, preferably a monolayer, and fixing the particles in a composition according to the present invention. The cytological, hematological, microbiological and histological fixative composition of the present invention contains an aldehyde cross-linker, a polyol and a detergent. The method of the present invention for preserving the particulate or histological specimen uses the fixative composition containing an aldehyde cross-linker, a polyol and a detergent.

L'invention concerne une composition fixative, l'utilisation de cette composition afin de préparer des spécimens cytologiques ou histologiques, ainsi qu'un procédé servant à préparer des particules, telles que des spécimens de cytologie, d'hématologie ou de microbiologie, afin de les examiner, ce qui consiste à recueillir ces particules en couche uniforme, de préférence une monocouche, et à les fixer dans ladite composition. Cette composition fixative cytologique, hématologique, microbiologique et histologique contient un agent de réticulation à base d'aldéhyde, un polyol et un détergent. Le procédé servant à conserver les particules ou le spécimen histologique met en application cette composition fixative contenant un agent de réticulation à base d'aldéhyde, un polyol et un détergent.

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