Cytological methods for detecting cancer

Details Cytological methods for detecting cancer Cytological methods for detecting cancer

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12Q 1/00 (2006.01) G01N 33/48 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2722424

The present invention relates to methods for diagnostics, detection or research analysis of cancer. In particular, the present invention is in the field of analysis of the levels of gene expression in normal or noncancerous cells because of their prox-imity to cancer cells. The present invention further provides for analysis of the altered gene expression levels in normal or noncancerous cells as an indicator of disease prognosis, staging and grading. The current invention is a means to increase the sensitiv-ity of needle core biopsies to detect the presence of cancer.

Cette invention concerne des procédés de diagnostic, de dépistage et d'analyse du cancer. En particulier, cette invention relève du domaine de l'analyse des niveaux d'expression génique dans des cellules normales ou non cancéreuses, compte tenu de leur proximité avec les cellules cancéreuses. Cette invention concerne, en outre, l'analyse des niveaux d'expression génique altérés dans des cellules normales ou non cancéreuses à titre d'indicateur de pronostic pathologique, de stade et de grade. Cette invention est un moyen pour augmenter la sensibilité des biopsies au trocart utilisées pour détecter la présence d'un cancer.

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