Cytomegalovirus vaccines and methods of production

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/245 (2006.01) A61P 31/22 (2006.01)

Patent

CA 2701727

Methods of increasing diversity in cytomegalovirus vaccines through the selection of cell type in which the virus is propagated, and the use of cytomegalovirus produced by those methods in the development of vaccine compositions, are disclosed. Vaccine compositions comprising CMV isolated from epithelial cells are also disclosed.

Cette invention a trait à des procédés d'augmentation de la diversité des vaccins dirigés contre le cytomégalovirus par sélection de types cellulaires dans lesquels le virus se propage; l'invention concerne également l'utilisation du cytomégalovirus produit par ces procédés dans le développement de compositions pour vaccins. L'invention concerne par ailleurs des compositions pour vaccins comprenant le CMV isolé à partir de cellules épithéliales.

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