Cytomodulating conjugates of members of specific binding pairs

Details Cytomodulating conjugates of members of specific binding pairs Cytomodulating conjugates of members of specific binding pairs

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2066810

s SANG-l3 US CYTOMODULATING CONJUGATES OF MEMBERS OF SPECIFIC BINDING PAIRS ABSTRACT OF THE DISCLOSURE Novel conjugates are provided comprising moiety capable of specifically binding to a target cell joined to a selective moiety for binding to an endogenous effector agent, capable of causing cell inactivation or cytotoxicity. Example of conjugates are a ligand for a surface membrane protein, e.g. IL-2 receptor, joined to a polysaccharide A or B antigen. The conjugates may be used to specifically destroy cells associated with a pathogenic condition. 17

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