Cytomodulating peptides for treating interstitial cystitis

Details Cytomodulating peptides for treating interstitial cystitis Cytomodulating peptides for treating interstitial cystitis

A - Human Necessities

61

K

A61K 38/08 (2006.01) A61K 38/02 (2006.01) A61K 38/03 (2006.01) A61P 13/10 (2006.01)

Patent

CA 2505922

The methods and compositions relate to treatment of disorders of the bladder. In particular, the methods provide for treatment of interstitial cystitis and related disorders. The methods further comprise treatment to affect various manifestations associated with interstitial cystitis, including, reducing histamine release, modulating Substance P expression, modulating nerve growth factor expression, modulating levels of various cytokines, and maintaining integrity of the urine/blood barrier.

L'invention concerne des méthodes et des compositions relatives au traitement de troubles de la vessie. Plus précisément, des méthodes de traitement de la cystite interstitielle et des troubles associés. Les méthodes de traitement ont également un effet sur diverses manifestations associées à la cystite interstitielle, notamment une réduction de la libération de l'histamine, une modulation de l'expression de la substance P, de l'expression du facteur de croissance du tissu nerveux et des niveaux de cytokines, ainsi qu'un maintien de l'intégrité de la barrière urine/sang.

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