Cytoprotective agents comprising monoamine oxidase inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/06 (2006.01) A61K 31/135 (2006.01) A61K 31/505 (2006.01) A61K 33/24 (2006.01) A61K 38/14 (2006.01)

Patent

CA 2284001

The present invention concerns the use of monoamine oxidase (MAO) inhibitors in the protection or rescue of normal cells from the toxic side effects caused by irradiation or the administration of chemotherapeutic agents such as certain anti-cancer agents. Deprenyl is a particularly preferred MAO inhibitor.

La présente invention concerne l'utilisation d'inhibiteurs de la monoamine-oxydase (MAO), dans la protection ou le sauvetage de cellules normales contre les effets secondaires toxiques provoqués par une irradiation ou l'administration d'agents chimiothérapeutiques tels que certains agents anti-cancéreux. Le déprényle est un inhibiteur de MAO particulièrement préféré.

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