Cytoprotective benzofuran derivatives

Details Cytoprotective benzofuran derivatives Cytoprotective benzofuran derivatives

C - Chemistry, Metallurgy

07

D

C07D 307/78 (2006.01) A61K 31/36 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07D 307/81 (2006.01) C07D 307/84 (2006.01) C07D 413/04 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2474974

Cytoprotective compounds, many of which are benzofuran derivatives are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.

L'invention porte sur des composés cytoprotecteurs dont un grand nombre d'entre eux sont des dérivés de benzofurane utiles dans le traitement de certains états ischémiques ou inflammatoires, tels que mais pas exclusivement, l'accident cérébrovasculaire, l'infarctus du myocarde, l'insuffisance cardiaque congestive et les maladies de la peau se caractérisant par une inflammation ou une lésion oxydative. Ces composés sont également utiles dans la fabrication de formulations pharmaceutiques et cosmétiques aptes à traiter ces états.

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