Cytotoxic agents comprising new taxanes

Details Cytotoxic agents comprising new taxanes Cytotoxic agents comprising new taxanes

C - Chemistry, Metallurgy

07

D

C07D 493/06 (2006.01) A61K 31/337 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2588587

The present invention relates to novel cytotoxic agents and their therapeutic use. More specifically, the invention relates to novel cytotoxic agents comprising taxanes and their therapeutic use. These novel cytotoxic agents have therapeutic use as a result of delivering the taxanes to a specific cell population in a targeted fashion by chemically linking the taxane to a cell binding agent.

L'invention concerne de nouveaux agents cytotoxiques et leur utilisation thérapeutique. De manière plus spécifique, l'invention concerne de nouveaux agents cytotoxiques présentant une utilisation thérapeutique grâce à l'administration de taxanes à une population de cellules spécifiques de manière ciblée par une liaison chimique du taxane à un agent de liaison de cellules.

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