A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/129
A61K 39/395 (2006.01) A61K 47/00 (2006.01) A61K 47/48 (2006.01) C07D 521/00 (2006.01) C07K 14/415 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1256796
ABSTRACT OF THE DISCLOSURE Immunotoxins formed by the covalent coupling of, on the one hand, the A chain of ricin, as such or correctly modified, with, on the other hand, an antibody or a fragment of an antibody, used in its natural form or correctly modified, which possesses the capacity to selectively recognize an antigen carried by the intended target cells. The coupling is effected either via a disulfide bond or via a thioether bond, with the limita- tion that, when the coupling is effected via a disulfide and one of the sulfur atoms is that belonging to the A chain of ricin, the other sulfur is bonded to the anti- body by a spacing structure which is itself bonded to a group of the protein other than an amine group.
483679
Gros Pierre
Jansen Franz
Sim & Mcburney
Societe Anonyme Styled: Sanofi
LandOfFree
Cytotoxic conjugates which can be used in therapy and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cytotoxic conjugates which can be used in therapy and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cytotoxic conjugates which can be used in therapy and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1220304