Cytotoxic depsipeptides

Details Cytotoxic depsipeptides Cytotoxic depsipeptides

C - Chemistry, Metallurgy

07

K

C07K 5/097 (2006.01) A61K 38/06 (2006.01) A61P 35/00 (2006.01) C12P 21/04 (2006.01)

Patent

CA 2529371

Compounds of general formula (I) wherein R1, R2, R3 are as defined and R4 groups are each independently selected from NR2, O and S; are of use in treatment of cancers.

L'invention concerne des composés de formule générale (I), dans laquelle R¿1?, R¿2?, R¿3? sont tels que définis dans le mémorandum descriptif; et chaque groupe R¿4? est indépendamment choisi parmi NR¿2?, O et S. Les composés de l'invention sont utiles dans le traitement de cancers.

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