Cytotoxic drug therapy

Details Cytotoxic drug therapy Cytotoxic drug therapy

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 16/30 (2006.01) C07K 16/40 (2006.01) C07K 16/46 (2006.01)

Patent

CA 2124218

A compound comprises a target cell-specific portion, such as an antibody specific to tumour cell antigens, and an inactivat- ing portion, such as an enzyme, capable of converting a substance which in its native state is able to inhibit the effect of a cytotox- ic agent into a substance which has less effect against said cytotoxic agent. The prolonged action of a cytotoxic agent at tumour sites is therefore possible whilst protecting normal tissues from the effects of the cytotoxic agent.

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