Cytotoxic factors for modulating cell death

Details Cytotoxic factors for modulating cell death Cytotoxic factors for modulating cell death

A - Human Necessities

61

K

A61K 38/44 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) C07K 14/195 (2006.01) C12N 5/00 (2006.01)

Patent

CA 2664797

Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death. The present inventors have found that different pathogens produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer.

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