Cytotoxic factors for modulating cell death

Details Cytotoxic factors for modulating cell death Cytotoxic factors for modulating cell death

C - Chemistry, Metallurgy

12

N

C12N 1/38 (2006.01) A61K 39/04 (2006.01) A61K 39/104 (2006.01) A61P 35/00 (2006.01) C07K 1/16 (2006.01) C07K 14/195 (2006.01) C07K 14/35 (2006.01) C12N 1/02 (2006.01) C12N 1/21 (2006.01) C12Q 1/04 (2006.01) G01N 33/50 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2436224

Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death. The present inventors have found that different pathogens produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer.

L'invention concerne des facteurs cytotoxiques trouvant une utilisation dans la modulation de la mort cellulaire, ainsi que leur utilisation dans des méthodes de traitement d'états pathologiques associés à la nécrose ou à l'apoptose. L'invention concerne également des méthodes d'identification d'agents actifs utiles dans le traitement d'états pathologiques associés à la mort cellulaire. On a découvert que différents agents pathogènes produisent un ou plusieurs facteurs cytotoxiques différents présentant une activité anticancéreuse. Des facteurs cytotoxiques sensiblement purs peuvent être utilisés dans une méthode de traitement d'une maladie infectieuse ou d'un cancer.

Affiliated with

Also associated with

Rating

Cytotoxic factors for modulating cell death does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cytotoxic factors for modulating cell death, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cytotoxic factors for modulating cell death will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1767155