Cytotoxic immunoglobulin

Details Cytotoxic immunoglobulin Cytotoxic immunoglobulin

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/00 (2006.01) C07K 16/32 (2006.01)

Patent

CA 2721614

The invention relates to a cytotoxic modular antibody with a molecular weight of up to 6OkD, specifically binding to a cell surface target with a binding affinity of Kd<10 -8 M, a method of producing such antibody and its use as a therapeutic.

Linvention concerne un anticorps modulaire cytotoxique ayant un poids moléculaire allant jusquà 60 kD, se liant spécifiquement à une cible de surface cellulaire avec une affinité de liaison de Kd < 10-8 M, un procédé de production dun tel anticorps et son utilisation en tant quagent thérapeutique.

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