Cytotoxic peptides modified by bulky or lipophilic moieties

Details Cytotoxic peptides modified by bulky or lipophilic moieties Cytotoxic peptides modified by bulky or lipophilic moieties

C - Chemistry, Metallurgy

07

K

C07K 14/79 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C07K 14/46 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2340326

The present invention provides a cytotoxic 7 to 25 mer peptide with three or more cationic residues which has one or more non-genetic bulky and lipophilic amino acids, as well as esters, amides, salts and cyclic derivatives thereof as well as methods of preparing the peptides, pharmaceutical compositions containing them and their use as medicaments, particularly as antibacterions or antitumoural agents.

L'invention concerne un peptide cytotoxique de 7 à 25 mer comportant trois ou plusieurs résidus cationiques possédant un ou plusieurs acides aminés non génétiques, volumineux et lipophiles, ainsi que des esters, des amides, des sels et des dérivés cycliques de ces peptides et des procédés servant à les préparer, des compositions pharmaceutiques les contenant et leur mise en application en tant que médicaments, en particulier, qu'agents antibactériens ou antitumoraux.

Affiliated with

Also associated with

Rating

Cytotoxic peptides modified by bulky or lipophilic moieties does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cytotoxic peptides modified by bulky or lipophilic moieties, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cytotoxic peptides modified by bulky or lipophilic moieties will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1602810