C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/05 (2006.01) A61K 39/245 (2006.01) A61P 37/04 (2006.01) C07K 7/04 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/04 (2006.01) C07K 14/045 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2185541
The present invention provides cytotoxic Epstein-Barr virus T-cell epitopes. The epitopes are selected from the group consisting of QAKWRLQTL, RYSIFFDY, HLAAQGMAY, YPLHEQHGM, SVRDRLARL, AVLLHEESM, VSFIEFVGW, FRKAQIQGL, PYLFWLAAI, TVFYNIPPMPL PGDQLPGFSDGRACPV, VEITPYKPTW, and variants thereof. In addition, the present invention provides compositions including those epitopes for use in inducing CTL's in a subject.
Epitopes de lymphocytes T cytotoxiques du virus Epstein-Barr. Les épitopes sont sélectionnés dans le groupe constitué de QAKWRLQTL, RYSIFFDY, HLAAQGMAY, YPLHEQHGM, SVRDRLARL, AVLLHEESM, VSFIEFVGW, FRKAQIQGL, PYLFWLAAI, TVFYNIPPMPL, PGDQLPGFSDGRACPV, VEITPYKPTW et de leurs variants. En outre, on a prévu des compositions renfermant ces épitopes et servant à induire des lymphocytes T cytotoxiques chez un sujet.
Burrows Jacqueline Margaret
Burrows Scott Renton
Kerr Beverley Mavis
Khanna Rajiv
Moss Denis James
Biotech Australia Pty. Limited
Commonwealth Scientific And Industrial Research Organisation
Csl Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The Council Of The Queensland Institute Of Medical Research
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