Cytotoxic t-cell epitopes of the papilloma virus l1-protein...

Details Cytotoxic t-cell epitopes of the papilloma virus l1-protein... Cytotoxic t-cell epitopes of the papilloma virus l1-protein...

C - Chemistry, Metallurgy

12

N

C12N 15/37 (2006.01) A61K 35/14 (2006.01) A61K 48/00 (2006.01) C07K 14/025 (2006.01) G01N 33/554 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2375802

The present invention relates to a papillomavirus T- cell epitope having an amino acid sequence ILVPKVSGL, RLVWACVGV, HLFNRAGTV, YLRREQMFV, TLQANKSEV, ILEDWNFGL, SLWLPSEATVYL, NLASSNYFPT, TLTADVMTYI, YLPPVPVSKV, YDLQFIFQL, ICWGNQLFV, FYNPDTQRL, MHGDTPTLH, ETTDLYCY, QAEPDRAHYN, SMVTSDAQI, and/or to a functionally active variant thereof, and also to their use in diagnostics and therapy.

L'invention concerne un épitope de cellule T du papillomavirus avec une séquence d'acides aminés du type ILVPKVSGL, RLVWACVGV, HLFNRAGTV, YLRREQMFV, TLQANKSEV, ILEDWNFGL, SLWLPSEATVYL, NLASSNYFPT, TLTADVMTYI, YLPPVPSKV, YDLQFIFQL, ICWGNQLFV, FYNPDTQRL, MHGDTPTLH, ETTDLYCY, QAEPDRAHYN, SMVTDSDAQI, et/ou une de ses variantes actives, et leur application en diagnostic et thérapie.

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