Cytotoxic t-lymphocyte antigen as cysteine protease inhibitor

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 9/64 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 14/81 (2006.01) C12N 9/99 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2140127

Disclosed are molecules which inhibit the proteolytic activity of cysteine proteases such as Cathepsin H, Cathepsin L and papain, and methods for using molecules which have the biological properties of cytotoxic T-lymphocyte antigen for inhibiting cysteine proteases and inhibiting proteoglycan degration.

On divulgue des molécules qui inhibent l'activité protéolytique des protéases à cystéine comme la cathepsine H, la cathepsine L et la papaïne, et des méthodes pour utiliser les molécules qui ont les propriétés biologiques de l'antigène du lymphocyte T cytotoxique pour inhiber les protéases à cystéine et pour inhiber la dégradation des protéoglycanes.

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