C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/12 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) G01N 33/567 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2643059
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDlVIAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMAB of the instant invention.
La présente invention concerne le diagnostic et le traitement de maladies cancéreuses, en particulier la médiation de la cytotoxicité des cellules tumorales; et plus particulièrement l'emploi d'anticorps modificateurs de maladies cancéreuses (CDlVIAB), éventuellement combinés à un ou plusieurs agents chimiothérapeutiques, dans le but d'initier la réponse cytotoxique. La présente invention concerne en outre des dosages de liaison utilisant les CDMAB de la présente invention.
Dacruz Luis A. G.
Findlay Helen P.
Hahn Susan E.
Hinton Paul
Kumar Shankar
Arius Research Inc.
F.hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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