Cytotoxicity mediation of cells evidencing surface...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/705 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 7/08 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2579905

This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMABs of the instant invention.

Diagnostic et traitement du cancer, plus particulièrement médiation de cytotoxicité de cellules tumorales, et plus concrètement utilisation d'anticorps modifiant le cancer (CDMAB), éventuellement en combinaison avec un ou plusieurs agents chimiothérapiques, tenant lieu de moyens d'initiation d'une réponse cytotoxique. Essais de liaison utilisant les CDMAB de l'invention.

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