Cytoxan antibodies and immunoassay

Details Cytoxan antibodies and immunoassay Cytoxan antibodies and immunoassay

C - Chemistry, Metallurgy

07

K

C07K 16/44 (2006.01) A61K 31/547 (2006.01) C07F 9/24 (2006.01) C07K 17/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2572671

Novel conjugates of protected aldehyde active metabolites of cyclophosphamide including reagents and immunogens thereof and monoclonal antibodies generated by these immunogens, said reagents and immunogens useful in immunoassays for the monitoring of the active metabolites of cyclophosphamide in patients being treated with cyclophosphamide.

L'invention concerne des conjugués de métabolites actifs à protection aldéhyde de cyclophosphamide qui comprennent des réactifs et des immunogènes correspondants, et elle concerne des anticorps monoclonaux produits par ces immunogènes, les réactifs et immunogènes en question étant utiles pour les immunoessais qui permettent le contrôle des métabolites actifs de cyclophosphamide chez les patients traités par cyclophosphamide.

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