D-form polypeptide which induces immune tolerance and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A01N 37/18 (2006.01) A61K 38/12 (2006.01) A61K 39/00 (2006.01) C07K 14/705 (2006.01) A61K 38/11 (2006.01)

Patent

CA 2368839

Methods and compositions useful in inhibiting integrin-associated diseases are provided. The compositions contain a polypeptide having one or more D-amino acids that inhibit integrin binding to its associated binding polypeptide. The compositions include retro-inverso polypeptides.

La présente invention concerne des techniques et des compositions utiles pour inhiber des maladies liées à l'intégrine. Ces compositions contiennent un polypeptide possédant un ou plusieurs amino acides D qui inhibent l'intégrine liée à ses polypeptides de liaison. Ces compositions comprennent des polypeptides rétro inverses.

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