D-homo steroids

Details D-homo steroids D-homo steroids

C - Chemistry, Metallurgy

07

J

260/4

C07J 63/00 (2006.01)

Patent

CA 1052768

ABSTRACT OF THE DISCLOSURE The D-homosteroids provided by the present invention have the following general formula Image (I) wherein R3 represents an oxo, (H,H) or (.alpha.-H, .beta.-O-acyl) grouping, R13 represents a lower alkyl group, R17a.beta. represents a hydrogen atom or an acyl or lower alkyl group and R17a.alpha. represents a hydrogen atom, a lower alkyl group or an ethynyl, 1-propynyl, vinyl, chloroethynyl, butadiynyl or propadienyl group and wherein the broken line in the A-ring denotes an addi- tional carbon-carbon bond in the 4,5- or 5(10)-position. The compounds are obtained by methods known per se and are hormonally active.

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