D-homosteroids

C - Chemistry – Metallurgy – 07 – J

Patent

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195/29, 260/4

C07J 63/00 (2006.01)

Patent

CA 1098897

Abstract of the Disclosure The specification discloses novel D-homosteroids, having inflammation-inhibiting activity, and having the formula Image (I) wherein the broken line in the 1,2-position denotes an optional carbon-carbon bond; R6 represents a hydrogen, fluorine or chlorine atom or a methyl group; R9 represents a hydrogen, fluorine or chlorine atom; and R17a represents a hydroxy or acyloxy group, with the proviso that, where R6 represents a hydrogen atom in a 11,17a-dihydroxy compound or R6 represents a fluorine atom in a 11,17a-dihydroxy-4-ene compound, R9 must represent a fluorine or chlorine atom.

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