D-homosteroids

C - Chemistry – Metallurgy – 07 – J

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C07J 63/00 (2006.01)

Patent

CA 1073448

ABSTRACT D-Homosteroids of the formula (I) Image wherein the broken line in the C ring represents an optional carbon-carbon bond, R3 represents an oxo, (.alpha.-H, .beta.-OH) or (.alpha.-H, .beta.-O-acyl) group, R18 represents a hydrogen atom or a methyl group, R17.alpha..beta. represents a hydrogen atom or an acyl, lower alkyl, cycloalkyl-(lower alkyl), benzyl, furfuryl or tetrahydropyranyl group and R17.alpha..alpha. represents a hydrogen atom or a lower alkyl, ethynyl, vinyl, allyl, methallyl, propadienyl, 1-propynyl, butadiynyl or chloroethynyl group, which are usefule for the manufacture of pharmaceutical preparations with hormonal activity and methods for the preparation thereof.

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