C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) C12N 9/86 (2006.01) C12P 13/04 (2006.01) C12P 21/02 (2006.01) C12P 41/00 (2006.01)
Patent
CA 2443377
The present invention relates to a novel D-hydantoinase from Ochrobactrum anthropi that enantio-selectively hydrolyzes D-hydantoins to their corresponding D-N-carbamoyl-amino acids; nucleic acids that encode for the enzyme; expression vectors including the nucleic acids; and host cells capable of expressing the enzyme.
La présente invention concerne un nouveau D-hydantoinase issu de Ochrobactrum anthropi, qui hydrolyse de manière énantiosélective des D-hydantoines en leurs D-N-carbamoyl-aminoacides correspondants. L'invention concerne des acides nucléiques codant pour l'enzyme; des vecteurs d'expression comprenant ces acides nucléiques; et des cellules hôtes pouvant exprimer l'enzyme.
Lowe David A.
Politino Michael
Romancik Guna
Tonzi Sean M.
Usher John J.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
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