A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/09 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2699215
The present invention is directed to the use of the peptide compound Pyr-His- Trp-Ser-Tyr-D-His(Bzl)-D-Leu-Arg- Pro-NHEt as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-D-Leu-Arg- Pro-NHEt optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
La présente invention concerne l'utilisation du composé peptidique Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-D-Leu-Arg-Pro-NHEt en tant qu'agent thérapeutique destiné à la prophylaxie et/ou au traitement du cancer, de maladies auto-immunes, de maladies fibreuses, de maladies inflammatoires, de maladies neurodégénératives, de maladies infectieuses, de maladies pulmonaires, de maladies cardiaques et vasculaires et de maladies métaboliques. L'invention concerne également des compositions pharmaceutiques, de préférence sous la forme d'un lyophilisat, d'une solution tampon liquide ou d'une préparation de lait maternel artificiel ou d'un substitut du lait maternel, contenant le peptide Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-D-Leu-Arg-Pro-NHEt, éventuellement avec au moins un véhicule, un cryoprotecteur, un lyoprotecteur, un excipient et/ou un diluant pharmaceutiquement acceptable.
Bacher Gerald
Bevec Dorian
Cavalli Fabio
Cavalli Vera
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Mondobiotech Laboratories Ag
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