C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 7/04 (2006.01) A61K 31/70 (2006.01) A61P 3/08 (2006.01) A61K 31/351 (2006.01) C07D 309/10 (2006.01)
Patent
CA 2574500
Disclosed are D-pyranosyl-substituted phenyls of general formula (I), wherein the radicals R1 to R5, X, Z, and R7a, R7b, R7c are defined as indicated in claim 1. Said phenyls have an inhibitory effect on the sodium-dependent glucose cotransporter SGLT. The invention further relates to medicaments for treating metabolism disorders.
La présente invention concerne des phényles D-pyranosyl-substitués de formule générale (I) dans laquelle les radicaux R1à R5, X, Z et R7a, R7b, R7c ont les correspondances indiquées dans la revendication 1. Ces composés ont une action d'inhibition sur les co-transporteurs de glucose dépendant du sodium (SGLT). L'invention a également pour objet des agents pharmaceutiques pour traiter des troubles du métabolisme.
Barsoumian Edward Leon
Eckhardt Matthias
Eickelmann Peter
Himmelsbach Frank
Thomas Leo
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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