D-xylopyranosyl-substituted phenyls, medicaments containing...

C - Chemistry – Metallurgy – 07 – H

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C07H 7/04 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2569915

The invention relates to D-xylopyranosyl-substituted phenyls of general formula (I) wherein the radicals R1 to R5, X, Z and R7a, R7b, R7c have the designations cited in patent claim 1, said phenyls having an inhibiting effect on the sodium-dependent glucose cotransporter SGLT. The invention also relates to medicaments for treating metabolic diseases.

L'invention concerne des phényles substitués par D-xylopyranosyle représentés par la formule générale (I), dans laquelle les groupes R1 à R5, X, Z et R7a, R7b, R7c sont tels que définis dans la revendication n°1. Ces composés possèdent une action inhibitrice sur le cotransporteur de glucose dépendant du sodium SGLT. La présente invention concerne également des médicaments destinés à traiter des maladies métaboliques.

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