Dab9 derivatives of lipopeptide antibiotics and methods of...

Details Dab9 derivatives of lipopeptide antibiotics and methods of... Dab9 derivatives of lipopeptide antibiotics and methods of...

C - Chemistry, Metallurgy

07

K

C07K 7/60 (2006.01) C07K 7/56 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2471458

The present invention provides Dab9 derivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.

La présente invention concerne des dérivés Dab?9¿ d'antibiotiques lipopeptidiques de type amphomycine qui présentent une activité antimicrobienne dirigée contre des bactéries Gram-positif, des techniques et des intermédiaires destinés à synthétiser ces composés et des techniques d'utilisation de ces composés dans une variété de contextes, notamment dans le traitement et la prévention des infections.

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