Ddavp antidiuretic and method therefor

Details Ddavp antidiuretic and method therefor Ddavp antidiuretic and method therefor

A - Human Necessities

61

K

167/103.46

A61K 38/11 (2006.01) A61K 9/20 (2006.01)

Patent

CA 1232839

ABSTRACT OF THE DISCLOSURE There is disclosed, in one aspect, an antidiuretic composition in oral dosage form for humans. This composition comprises an antidiuretically effective amount of 1-deamino-8-D- arginine vasopressin (DDAVP) and a pharmaceutically acceptable carrier. The composition is capable of dissolving and being absorbed in the gastrointestinal tract of a human. The composition is used in tablet, capsule, or other generally accepted oral dosage form and generally from about 50 to about 200 micrograms of DDAVP is used per unit dosage. In another aspect, there is disclosed a method for treating diabetes insipidus. This method comprises orally administering an antidiuretically effective amount of DDAVP to a human. The DDAVP is substantially dissolved and absorbed in the gastro- intestinal tract of the person so treated.

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