De-esterification process for cephalosporins

Details De-esterification process for cephalosporins De-esterification process for cephalosporins

C - Chemistry, Metallurgy

07

D

260/100

C07D 501/14 (2006.01) C07D 501/04 (2006.01) C07D 501/20 (2006.01) C07D 501/60 (2006.01) A61K 31/545 (2006.01)

Patent

CA 1076559

Abstract of the Disclosure This invention provides a process wherein the p-nitrobenzyl esters of cephalosporins are reductively cleaved to provide the antibiotic cephalosporins as the free acids in good yields.

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