De(mycinosyloxy)tylosin derivatives

C - Chemistry – Metallurgy – 12 – P

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C12P 19/62 (2006.01) C07H 17/08 (2006.01)

Patent

CA 1211731

ABSTRACT 20-Dihydro-20-deoxy-23-de(mycinosyloxy)- tylosin (20-deoxo-DMOT), acyl ester derivatives, and their acid addition salts are useful intermediates and antibacterial agents. Methods of preparing 20-deoxo- DMOT and 5-O-mycaminosyltylactone by fermentation of Streptomyces fradiae ATCC 31733 are included.

431623

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