De-n-acetyl sialic acid antigens, antibodies thereto, and...

Details De-n-acetyl sialic acid antigens, antibodies thereto, and... De-n-acetyl sialic acid antigens, antibodies thereto, and...

A - Human Necessities

61

K

A61K 39/395 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2634755

The present invention generally provides compositions methods and composition relating to the diagnosis and/or treatment of cancers having a cell surface de- N-acetylated sialic acid antigen, e.g., an at least partially de-N-acetylated ganglioside and/or a de-N-acetylated sialic acid-modified cell surface protein.

L'invention porte sur des procédés de composition et des compositions ayant trait au diagnostic et/ou au traitement de cancers présentant une surface cellulaire d'un antigène d'acide sialique dés-N-acétylé, par exemple une protéine de surface cellulaire modifiée par du ganglioside au moins partiellement dés-N-acétylé et/ou de l'acide sialique dés-N-acétylé.

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