C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/199, 195/43,
C12N 5/02 (2006.01) A61K 31/70 (2006.01) C07H 15/10 (2006.01) C12N 5/00 (2006.01)
Patent
CA 1339488
Substantially pure gangliosides containing de-N-acetyl-sialic acid. A culture medium for stimulating growth of human and animal cells comprising: (1) essential nutrients for cell growth, and (2) a cell growth stimulatory amount of one or more gangliosides containing de-N-acetyl-sialic acid. A method for stimulating growth of human and animal cells cultured in vitro comprising contacting said cells in culture with a cell growth stimulatory amount of one or more gangliosides containing de-N-acetyl-sialic acid. A medicament for stimulating growth of human and animal cells comprising: (1) a cell growth stimulatory amount of one or more growth stimulators selected from the group consisting of gangliosides containing de-N-acetyl-sialic acid, substances that promote synthesis of gangliosides containing de-N-acetyl-sialic acid and pharmaceutically acceptable salts thereof: and (2) a pharmaceutically acceptable carrier, diluent or excipient. A method for stimulating growth of human and animal cells in vivo comprising contacting said cells with a cell growth stimulatory amount of gangliosides containing de-N-acetyl-sialic acid, substances that promote synthesis of gangliosides containing de-N-acetyl-sialic acid, and pharmaceutically acceptable salts thereof. A medicament for inhibiting growth of human and animal cells comprising: (1) a cell growth inhibitory amount of one or more growth inhibitors that block synthesis of gangliosides containing de-N-acetyl-sialic acid or pharmaceutically acceptable salts thereof; and (2) a pharmaceutically acceptable carrier, diluent or excipient. A method for inhibiting growth of human and animal cells in vivo comprising contacting said cells with a cell growth inhibitory amount of one or more growth inhibitors that block synthesis of gangliosides containing de-N-acetyl-sialic acid or pharmaceutically acceptable salts thereof.
590777
Dohi Taeko
Hakomori Sen-Itiroh
Hanai Nobuo
Nojiri Hisao
Nores Gustavo A.
Dohi Taeko
G. Ronald Bell & Associates
Hakomori Sen-Itiroh
Hanai Nobuo
Nojiri Hisao
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