C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/70 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12P 21/02 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2331781
De novo DNA cytosine methyltransferase polynucleotides and polypeptides and methods for producing said polypeptides are disclosed. Also disclosed are methods for utilizing de novo DNA cytosine methyltransferase polynucleotides and polypeptides in diagnostic assays, for an in vitro DNA methylation application and therapeutic applications such as the treatment of neoplastic disorders.
La présente invention concerne, d'une part des polynucléotides ainsi que des polypeptides à cytosine méthyltransférase d'ADN adventif, et d'autre part des procédés de production de ces polypeptides. L'invention concerne également des procédés permettant d'utiliser dans des dosages de diagnostic ces polynucléotides et polypeptides à cytosine méthyltransférase d'ADN adventif, et ce, dans le cadre d'applications à méthylation in vitro de l'ADN et d'applications thérapeutiques telles que le traitement de troubles néoplasiques.
Li En
Okano Masaki
Xie Shaoping
Mbm Intellectual Property Law Llp
The General Hospital Corporation
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