C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 11/02 (2006.01) A61K 35/12 (2006.01) A61L 27/38 (2006.01) C12N 11/04 (2006.01) C12Q 1/02 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2659673
It has been discovered that vascularized tissue or organs can be engineered by combined actions of tissue progenitor cells and vascular progenitor cells. Provided herein are compositions and methods directed to engineered vascularized tissue or organs formed by introducing tissue progenitor cells and vascular progenitor into or onto a biocompatible scaffold of matrix material. Also provided are methods of treating tissue defects via grafting of such compositions into subjects in need thereof.
On a découvert que des tissus ou organes vascularisés peuvent être construits par les actions combinées de cellules progénitrices des tissus et de cellules progénitrices vasculaires. L'invention concerne des compositions et des procédés concernant des tissus ou organes vascularisés construits formés en introduisant des cellules progénitrices des tissus et des cellules progénitrices vasculaires dans ou sur une structure support biocompatible en matière matrice. L'invention concerne également des procédés de traitement de défauts dans des tissus via le greffage de telles compositions sur des sujets qui en ont besoin.
Columbia University
Kirby Eades Gale Baker
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