Death domain containing receptor 5

Details Death domain containing receptor 5 Death domain containing receptor 5

C - Chemistry, Metallurgy

12

N

C12N 15/28 (2006.01) A61K 31/475 (2006.01) A61K 31/519 (2006.01) A61K 31/704 (2006.01) A61K 31/7064 (2006.01) A61K 31/7068 (2006.01) A61K 33/24 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C12N 5/00 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/567 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2644454

The present invention relates to novel Death Domain Containing Receptor-5 (DR5) proteins which are members of the tumor necrosis (TNF) receptor family, and have now been shown to bind TRAIL. In particular, isolated nucleic acid molecules are provided encoding the human DR5 proteins. DR5 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying antagonists and antagonists of DR5 activity.

Affiliated with

Also associated with

Rating

Death domain containing receptor 5 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Death domain containing receptor 5, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Death domain containing receptor 5 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1519528