Deazapurine derivatives

Details Deazapurine derivatives Deazapurine derivatives

C - Chemistry, Metallurgy

07

D

260/242.5

C07D 487/04 (2006.01)

Patent

CA 1181399

Abstract of the Disclosure Novel deazapurine derivatives of the formula: Image wherein R1 is C1-18 alkyl which may be substituted with di-C1-3 alkyl amino; C1-18 alkenyl; C3-8 cyloalkyl; C5-8 cyclo- alkenyl; C7-13 aralkyl which may be substituted with C1-4 alkoxy, C1-4 alkanoyl, C2-4 alkoxycarbonyl, hydroxy, amino,nitro, trifluoromethyl or C1-4 alkanoylamido; or C6-10 aryl and R2 is hydrogen or C7-13 aralkyl or, R1 and R2, taken together with the adjacent nitrogen atom, form a piperidine ring, and salt thereof are selectively taken up by tumor cells and have antitumor activity.

412165

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