Decahydroquinolinol derivatives, process for preparing them...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/22 (2006.01) C07D 215/233 (2006.01)

Patent

CA 1144170

ABSTRACT OF THE DISCLOSURE New decahydroquinolinol derivatives and process for preparing the same. This invention relates to new decahydro- quinolinol derivatives corresponding to the general formula : Image and pharmaceutically acceptable acid addition salts thereof, in which R1 represents hydrogen, a methyl, ethyl, n-propyl, n- butyl or phenyl radical or a phenyl radical having one sub- stituent or two identical or different substituents selected from chlorine, bromine atoms and a methyl group, Ar represents a phenyl or naphthyl radical or a phenyl radical having one substituent or two identical or different substituents selected from fluorine, chlorine and bromine atoms and methyl, methoxy, acetyl and cyano groups, X represents oxygen or sulphur, and n represents 2 or 3. These derivatives are useful as anti- arrhthmic and local anaesthetic agents.

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