Decellularisation of matrices

Details Decellularisation of matrices Decellularisation of matrices

A - Human Necessities

61

L

A61L 27/36 (2006.01) A01N 1/02 (2006.01)

Patent

CA 2447847

A method of preparing matrices or tissue engineered biomaterials for implantation, and in particular to a method of improving decellularisation of matrices or tissue engineered biomaterials prior to implantation. The method employs a single anionic detergent in combination with protease inhibitors.

Cette invention concerne une méthode de préparation, en vue d'une implantation, de matrices ou de biomatériaux obtenus par génie tissulaire en vue d'implantations, et singulièrement une méthode permettant d'améliorer la décellularisation de matrices ou de biomatériaux obtenus par génie tissulaire avant implantation. Cette méthode repose sur l'emploi d'un détergeant anionique unique avec des inhibiteurs de protéase.

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