Decontamination of surfaces contaminated with prion-infected...

A - Human Necessities – 61 – L

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A61L 2/20 (2006.01) C11D 3/39 (2006.01) C11D 7/06 (2006.01)

Patent

CA 2462807

A surface which carries a material which is infected with prions is cleaned with an alkaline cleaning solution to remove as much proteinaceous material as possible from the surface. The solution contains an alkaline cleaning agent which attacks prions remaining on the surface and which attacks prions removed from the surface during the cleaning step. After the cleaning step, the surface is exposed to a strong gaseous oxidant, preferably hydrogen peroxide vapor. The hydrogen peroxide or other strong oxidant attacks the prions, particularly the unclumped prion strands, deactivating the prions.

L'invention concerne une surface portant une substance infectée par des prions, que l'on nettoie à l'aide d'une solution de nettoyage alcaline en vue d'enlever le plus possible de matière protéique de ladite surface. Ladite solution contient un agent de nettoyage alcalin qui attaque les prions restant sur la surface ainsi que les prions évacués de celle-ci pendant le nettoyage. La surface est ensuite exposée à un oxydant gazeux puissant, de préférence de la vapeur de peroxyde d'hydrogène. Le peroxyde d'hydrogène ou d'autres oxydants puissants attaque les prions, en particulier les brins de prions non agglutinés, et neutralise les prions.

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