Decoy composition for treating and preventing inflammatory...

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 9/127 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 45/00 (2006.01) A61P 1/16 (2006.01) A61P 13/02 (2006.01) A61P 13/08 (2006.01) A61P 13/10 (2006.01) A61P 13/12 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2493902

It is intended to efficiently treat an inflammatory disease without causing side effects. This object can be achieved by providing a medicinal composition for treating and preventing an inflammatory disease and disorders and disorders caused by the disease and the disorders which contains at least one decoy of NF-.kappa.B or an analogous transcriptional factor and a pharmaceutically acceptable carrier; and a method of treating and preventing an inflammatory disease and disorders and disorders caused by the disease and the disorders which comprises the step of administering to a patient a composition containing at least one decoy of NF-.kappa.B or an analogous transcriptional factor and a pharmaceutically acceptable carrier.

On a l'intention de traiter efficacement une affection inflammatoire sans provoquer d'effets secondaires. A cet effet, on propose une composition médicinale permettant de traiter et de prévenir une affection et des troubles inflammatoires ainsi que des troubles imputables à l'affection et aux troubles, cette composition comprenant au moins un leurre du NF-?B ou un facteur de transcription analogue et un vecteur pharmaceutiquement admis. L'invention concerne également un procédé permettant de traiter et de prévenir une affection et des troubles inflammatoires et des troubles provoqués par l'affection et les troubles, ce procédé comprenant une opération d'administration au patient d'une composition contenant au moins un leurre du NF-?B ou un facteur de transcription analogue et un vecteur pharmaceutiquement admis.

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