A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01) A61K 31/197 (2006.01) A61K 31/198 (2006.01)
Patent
CA 2565095
The present invention relates to the treatment or prevention of glutamatergic toxicity by the administration of effective amounts of branched chain .alpha.- keto acids alone or in combination with other antiglutamate agents such as L- methionine S-sulfoximine, L-ethionine S-sulfoximine, and glufosinate. In particular, the present invention relates to the treatment or prevention of diseases or conditions which are characterized by increased levels of brain neuronal glutamate.
L'invention concerne le traitement ou la prévention de la toxicité glutamatergique par administration de doses efficaces d'acides .alpha.-céto à chaîne ramifiée seuls ou en combinaison avec d'autres agents antiglutamate tels que L-méthionine S-sulfoximine, L-éthionine S-sulfoximine et glufosinate. Plus précisément, l'invention concerne le traitement ou la prévention de maladies ou d'états se caractérisant par des taux accrus de glutamate neuronal cérébral.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Odessa Pharma Llc
LandOfFree
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