Dedifferentiated, programmable stem cells of monocytic...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 5/0789 (2010.01) C12N 5/0786 (2010.01) A61K 35/12 (2006.01) A61L 27/38 (2006.01)

Patent

CA 2479110

The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.

La présente invention concerne la production de cellules souches dédifférenciées adultes programmables provenant de monocytes humains, à laquelle on parvient en cultivant des monocytes dans un milieu de culture contenant du M-CSF et de l'IL-3. L'invention se rapporte en outre à des préparations pharmaceutiques contenant les cellules souches dédifférenciées programmables précitées, et à l'utilisation de ces dernières dans la production de cellules et tissus cibles.

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