Defective packaging non-oncoviral vectors based on mpmv and hiv

Details Defective packaging non-oncoviral vectors based on mpmv and hiv Defective packaging non-oncoviral vectors based on mpmv and hiv

C - Chemistry, Metallurgy

12

N

C12N 15/867 (2006.01) A61K 48/00 (2006.01) C12N 7/01 (2006.01) C12N 15/49 (2006.01)

Patent

CA 2557882

Novel vectors are capable of producing MPMV (Mason-Pfizer Monkey Virus) proteins but not of packaging MPMV RNA, and the information about the packaging signal in MPMV and HIV can be used to create MPMV and HIV vectors that are capable of transferring foreign genes, e.g. for use in gene therapy.

L'invention porte sur de nouveaux vecteurs capables de produire des protéines de MPMV (virus simien de Mason-Pfizer), mais pas d'empaqueter l'ARN du virus. Les données sur le signal d'empaquetage du MPMV et du VIH peuvent servir à créer des vecteurs à base de MPMV et de VIH en mesure de transférer des gènes étrangers, p. ex. pour une utilisation en thérapie génique.

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