Defective viral vaccine particles obtained in vivo or ex vivo

Details Defective viral vaccine particles obtained in vivo or ex vivo Defective viral vaccine particles obtained in vivo or ex vivo

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 39/12 (2006.01) A61K 48/00 (2006.01) C07K 14/16 (2006.01) C12N 7/04 (2006.01) C12N 15/867 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2251027

A vaccine consisting of defective viral particles as obtained in vivo or ex vivo from individuals infected or infectable by a virus, following expression of genes borne by a vector or combination of vectors, and including at least the structural genes required to constitute the viral particle.

La présente invention se rapporte à un vaccin constitué de particules virales défectives telles qu'obtenues in vivo ou ex vivo chez des individus infectés ou susceptibles d'être infectés par un virus, après expression des gènes portés par un vecteur ou une association de vecteurs et comprenant au moins les gènes de structure nécessaires à la constitution de la particule virale.

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