Defined coating with recombinant fusion proteins composed of...

A - Human Necessities – 61 – K

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A61K 39/44 (2006.01) G01N 33/531 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2061574

BEHRINGWERKE AKTIENGESELLSCHAFT 91/B 003 - Ma 804 Dr. Lp/Wr Abstract of the disclosure Defined coating with recombinant fusion proteins composed of constant fusion partner and variable antigen portion in diagnostic test systems The invention relates to solid support materials, for example, microtiter plates, beads or microbeads, magnetic particles, films, filter papers and the like, which are coated with antibodies against recombinant fusion pro- teins, and to processes for the reproducible and defined coating of these surfaces with such recombinant fusion proteins. The recombinant fusion proteins contain a constant fusion partner and a variable antigen part which constitutes the specificity of the test system. The abovementioned antibodies are directed against the constant fusion partner, that is to say the part of each fusion protein which is intrinsically not of analytical interest and uniform.

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